Historisk bakgrund Gustav Bohlin Antibiotika och resistens
Före Penicillin Louis PasteurRobert Koch NP 1905 Gerhard Domagk NP 1939
Sir Alexander Fleming Fältläkare 1:a världskriget Mytomspunnen upptäckt utav penicillin
Penicillium notatum + Effektivt mot bakterietillväxt + Skonsamt mot kroppens egna celler - Svårt att isolera och rena fram stora mängder
Efter Penicillin Selman Waksman NP 1952 Idag: 60-tal olika antibiotika tillgängligt i Sverige. Penicillin fortfarande viktigast och mest använt. NP 2009
“But I would like to sound one note of warning… …It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body.” “But I would like to sound one note of warning… …It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body.” Sir Alexander Fleming, 1945